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Prevalence and clinical characterization of MMR-D/MSI extra-colonic cancers among germline PMS2 mutation carriers.

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1527Background: PMS2-associated Lynch syndrome (LS) may have a more modest phenotype than that associated with other mismatch repair (MMR) genes (MLH1, MSH2, MSH6, EPCAM). Recent studies suggest li... Click to show full abstract

1527Background: PMS2-associated Lynch syndrome (LS) may have a more modest phenotype than that associated with other mismatch repair (MMR) genes (MLH1, MSH2, MSH6, EPCAM). Recent studies suggest li...

Keywords: clinical characterization; pms2; characterization mmr; mmr msi; msi extra; prevalence clinical

Journal Title: Journal of Clinical Oncology
Year Published: 2020

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