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3624Background: Adavosertib, a first-in-class Wee1 kinase inhibitor, abrogates G2/M cell cycle arrest causing premature mitosis and DNA replication stress, yielding enhanced DNA damage. Here we rep... Click to show full abstract
3624Background: Adavosertib, a first-in-class Wee1 kinase inhibitor, abrogates G2/M cell cycle arrest causing premature mitosis and DNA replication stress, yielding enhanced DNA damage. Here we rep...
Keywords:
inhibitor;
analysis biomarker;
identification phase;
biomarker identification;
tumor genomic;
genomic analysis
Journal Title: Journal of Clinical Oncology
Year Published: 2020
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Journal Title: Journal of Clinical Oncology
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!