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Influence of BRCA pathogenic variants in the benefit of secondary cytoreductive surgery.

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6076Background: Germline BRCA pathogenic variants are present in 15% to 25% of ovarian carcinoma patients. These tumors are more sensitive to platinum and PARP inhibitor therapy and have a better… Click to show full abstract

6076Background: Germline BRCA pathogenic variants are present in 15% to 25% of ovarian carcinoma patients. These tumors are more sensitive to platinum and PARP inhibitor therapy and have a better p...

Keywords: pathogenic variants; variants benefit; benefit secondary; influence brca; brca pathogenic

Journal Title: Journal of Clinical Oncology
Year Published: 2020

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