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The impact of tumor hypoxia on the clinical efficacy of anti-PD-1 mAb treatment in recurrent/metastatic HNSCC patients (R/M).

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6546Background: Anti-PD-1 mAbs have changed the landscape of R/M HNSCC treatment, but physical, immunologic, and metabolic barriers present in the tumor microenvironment are likely drivers of low r... Click to show full abstract

6546Background: Anti-PD-1 mAbs have changed the landscape of R/M HNSCC treatment, but physical, immunologic, and metabolic barriers present in the tumor microenvironment are likely drivers of low r...

Keywords: treatment; impact tumor; hypoxia clinical; hnscc; tumor hypoxia

Journal Title: Journal of Clinical Oncology
Year Published: 2020

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