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Interim analysis (IA) of OPTIC: A dose-ranging study of three ponatinib (PON) starting doses.

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7502Background: In PACE (NCT01207440) heavily pretreated patients (pts) with chronic-phase CML (CP-CML) had deep, lasting responses to PON; long-term follow-up showed increasing rates of arterial o... Click to show full abstract

7502Background: In PACE (NCT01207440) heavily pretreated patients (pts) with chronic-phase CML (CP-CML) had deep, lasting responses to PON; long-term follow-up showed increasing rates of arterial o...

Keywords: dose ranging; analysis optic; interim analysis; ranging study; optic dose; study three

Journal Title: Journal of Clinical Oncology
Year Published: 2020

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