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Characterization of 1,387 NSCLCs with MET exon 14 (METex14) skipping alterations (SA) and potential acquired resistance (AR) mechanisms.

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9511Background: METex14 SA are oncogenic drivers in NSCLC. Due to the numerous sites around ex14 that bind the spliceosome complex, many variations can result in deleterious alterations (alts). We ... Click to show full abstract

9511Background: METex14 SA are oncogenic drivers in NSCLC. Due to the numerous sites around ex14 that bind the spliceosome complex, many variations can result in deleterious alterations (alts). We ...

Keywords: nsclcs met; exon metex14; characterization 387; metex14; 387 nsclcs; met exon

Journal Title: Journal of Clinical Oncology
Year Published: 2020

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