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Characterization of the immune tumor microenvironment of HER2-positive breast cancer following treatment with entinostat and immune checkpoint inhibition.

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e15061Background: HER2+ breast cancers are known to be less-immunogenic and associated with low response rates to immune checkpoint inhibitors (ICIs). A combination of immunosuppressive signals tha... Click to show full abstract

e15061Background: HER2+ breast cancers are known to be less-immunogenic and associated with low response rates to immune checkpoint inhibitors (ICIs). A combination of immunosuppressive signals tha...

Keywords: immune checkpoint; breast; immune tumor; characterization immune; tumor microenvironment

Journal Title: Journal of Clinical Oncology
Year Published: 2020

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