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A phase I study of the novel immunotoxin, MT-5111, in subjects (subj) with HER-2 positive tumors: Interim results.

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e15567Background: Engineered toxin bodies (ETBs), composed of a Shiga-like Toxin A subunit genetically fused to antibody-like binding domains, can force receptor internalization, self-route through... Click to show full abstract

e15567Background: Engineered toxin bodies (ETBs), composed of a Shiga-like Toxin A subunit genetically fused to antibody-like binding domains, can force receptor internalization, self-route through...

Keywords: study novel; 5111 subjects; immunotoxin 5111; subjects subj; novel immunotoxin; phase study

Journal Title: Journal of Clinical Oncology
Year Published: 2020

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