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Metabolism-based GP-2250 in combination with gemcitabine as a novel approach to pancreatic cancer: A mouse xenograft study.

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e16750Background: GP-2250, a novel oxathiazine derivative, displayed apoptotic cytotoxicity against various tumor cell lines but not normal cells. It was therefore tested whether its antineoplastic... Click to show full abstract

e16750Background: GP-2250, a novel oxathiazine derivative, displayed apoptotic cytotoxicity against various tumor cell lines but not normal cells. It was therefore tested whether its antineoplastic...

Keywords: metabolism based; gemcitabine novel; combination gemcitabine; based 2250; novel approach; 2250 combination

Journal Title: Journal of Clinical Oncology
Year Published: 2020

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