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Pembrolizumab in combination with the oncolytic virus pelareorep in patients progressing on systemic chemotherapy for advanced pancreatic adenocarcinoma: A phase II study.

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e16789Background: Pelareorep is an intravenously delivered oncolytic reovirus that can induce a T-cell-inflamed phenotype in pancreatic ductal adenocarcinoma (PDAC). Analysis of tumor tissue from p... Click to show full abstract

e16789Background: Pelareorep is an intravenously delivered oncolytic reovirus that can induce a T-cell-inflamed phenotype in pancreatic ductal adenocarcinoma (PDAC). Analysis of tumor tissue from p...

Keywords: oncolytic virus; virus pelareorep; pelareorep patients; combination oncolytic; pembrolizumab combination; adenocarcinoma

Journal Title: Journal of Clinical Oncology
Year Published: 2020

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