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Effect of inducing HR deficiency using AVB500, a receptor tyrosine kinase AXL inhibitor, on response to olaparib in uterine serous cancer.

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e18108Background: Evidence suggests DNA repair is a therapeutic target in endometrial cancer (EC). Given this, we determined whether combination therapy with AVB500, an AXL inhibitor, could improve... Click to show full abstract

e18108Background: Evidence suggests DNA repair is a therapeutic target in endometrial cancer (EC). Given this, we determined whether combination therapy with AVB500, an AXL inhibitor, could improve...

Keywords: deficiency using; inducing deficiency; axl inhibitor; cancer; effect inducing

Journal Title: Journal of Clinical Oncology
Year Published: 2020

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