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Different efficacy of osimertinib in pre-TKI treated NSCLC patients with brain metastases harboring EGFR exon 19del and L858R mutant.

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e21667Background: Previous studies suggested that the efficacy of osimertinib was better in patients with epidermal growth factor receptor (EGFR) exon 19 deletion (ex19del) than exon 21 Leu858Arg (... Click to show full abstract

e21667Background: Previous studies suggested that the efficacy of osimertinib was better in patients with epidermal growth factor receptor (EGFR) exon 19 deletion (ex19del) than exon 21 Leu858Arg (...

Keywords: egfr exon; osimertinib pre; different efficacy; efficacy osimertinib

Journal Title: Journal of Clinical Oncology
Year Published: 2020

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