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Irinotecan and temozolomide upfront and in relapsed Ewing sarcoma: A translational study on MGMT (O6-methylguanine–DNA methyltransferase) and ABCG2 (MGMTLiberati).

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e23564Background: Activity of temozolomide (TEM) and irinotecan (IRI) in recurrent Ewing sarcoma (EWS) was demonstrated. Few data are available on TEMIRI use upfront. Biological predictive factors ... Click to show full abstract

e23564Background: Activity of temozolomide (TEM) and irinotecan (IRI) in recurrent Ewing sarcoma (EWS) was demonstrated. Few data are available on TEMIRI use upfront. Biological predictive factors ...

Keywords: sarcoma translational; temozolomide upfront; ewing sarcoma; irinotecan temozolomide; relapsed ewing; upfront relapsed

Journal Title: Journal of Clinical Oncology
Year Published: 2020

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