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Phase I study of SEA-CD40, gemcitabine, nab-paclitaxel, and pembrolizumab in patients with metastatic pancreatic ductal adenocarcinoma (PDAC).

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TPS4671Background: SEA-CD40 is an investigational non-fucosylated, humanized IgG1 monoclonal antibody directed against CD40, a co-stimulatory receptor expressed on antigen-presenting cells (APCs). ... Click to show full abstract

TPS4671Background: SEA-CD40 is an investigational non-fucosylated, humanized IgG1 monoclonal antibody directed against CD40, a co-stimulatory receptor expressed on antigen-presenting cells (APCs). ...

Keywords: sea; study sea; cd40 gemcitabine; gemcitabine nab; phase study; sea cd40

Journal Title: Journal of Clinical Oncology
Year Published: 2020

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