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349Background: Resistance to ADT is associated with a gain of function mutation in the 3β-HSD enzyme, which catalyzes extragonadal/intratumoral DHT synthesis. As androgen signaling is known to upre... Click to show full abstract
349Background: Resistance to ADT is associated with a gain of function mutation in the 3β-HSD enzyme, which catalyzes extragonadal/intratumoral DHT synthesis. As androgen signaling is known to upre...
Keywords:
cell intrinsic;
androgen;
intrinsic androgen;
biosynthesis hydroxy;
androgen biosynthesis;
tumor cell
Journal Title: Journal of Clinical Oncology
Year Published: 2020
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Journal Title: Journal of Clinical Oncology
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!