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Initial results from a first in human trial incorporating accelerated dose titration of a novel immune stimulating oncolytic virus - VG161.

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e14574Background: Oncolytic virus (OV) can specifically replicate in cancer cells causing cell lysis. Together with the expression of immune stimulating payloads, OV can induce an anti-tumor immune... Click to show full abstract

e14574Background: Oncolytic virus (OV) can specifically replicate in cancer cells causing cell lysis. Together with the expression of immune stimulating payloads, OV can induce an anti-tumor immune...

Keywords: initial results; immune stimulating; results first; oncolytic virus

Journal Title: Journal of Clinical Oncology
Year Published: 2021

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