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A first-in-human phase I study of ATR inhibitor M1774 in patients with solid tumors.

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TPS3153Background: Ataxia telangiectasia and Rad3-related (ATR) protein kinase plays a critical role in the DNA damage response by sensing and responding to DNA replication stress, and by inducing ... Click to show full abstract

TPS3153Background: Ataxia telangiectasia and Rad3-related (ATR) protein kinase plays a critical role in the DNA damage response by sensing and responding to DNA replication stress, and by inducing ...

Keywords: first human; study atr; atr inhibitor; inhibitor m1774; human phase; phase study

Journal Title: Journal of Clinical Oncology
Year Published: 2021

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