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Key Points Question Is it possible to create and validate a nomogram for prediction of freedom from biochemical failure (FFBF) among patients with prostate cancer after prostate-specific membrane antigen positron-emission… Click to show full abstract
Key Points Question Is it possible to create and validate a nomogram for prediction of freedom from biochemical failure (FFBF) among patients with prostate cancer after prostate-specific membrane antigen positron-emission tomography (PSMA-PET)–guided salvage radiotherapy after prostatectomy? Findings This cohort study included 1029 patients (training set, 708; internal validation set, 271; external outlier validation set, 50) with a median follow-up of 32 months from a retrospective multicenter cohort. The nomogram concordance index was 0.72 for FFBF in the internal validation set and 0.67 for FFBF in the external outlier validation set. Meaning This study suggests that a nomogram can be created and validated for FFBF prediction among patients with prostate cancer after PSMA-PET–guided salvage radiotherapy.
Journal Title: JAMA Network Open
Year Published: 2023
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