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Spontaneous remission lasting 3 decades in myelin oligodendrocyte glycoprotein disease.

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In February 2017, a 52-year-old woman was brought to our clinic after abrupt right vision loss. Four days later, both eyes were affected, bilateral optic neuritis (ON) was diagnosed, and… Click to show full abstract

In February 2017, a 52-year-old woman was brought to our clinic after abrupt right vision loss. Four days later, both eyes were affected, bilateral optic neuritis (ON) was diagnosed, and the patient was treated with a short course of corticosteroids. Her medical history revealed she was admitted at the age of 18 years with severe paraparesis, followed 4 weeks later by right vision loss. With a short course of corticosteroids, the patient achieved full recovery, but no etiology was found. Myelin oligodendrocyte glycoprotein (MOG)-IgG positivity and aquaporine-4 antibodies (AQP4-IgG) absence (cell-based immunoassay, analysed by microscopy) were confirmed in the present attack (figure for case description).

Keywords: spontaneous remission; myelin oligodendrocyte; oligodendrocyte glycoprotein; remission lasting; lasting decades

Journal Title: Neurology: Clinical Practice
Year Published: 2019

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