Paracelsus is famous for saying “Poison is in everything, and no thing is without poison. The dosage makes it either a poison or a remedy.” The report in this issue… Click to show full abstract
Paracelsus is famous for saying “Poison is in everything, and no thing is without poison. The dosage makes it either a poison or a remedy.” The report in this issue of Neurology® by Racette et al.1 titled “Dose-dependent progression of parkinsonism in manganese-exposed welders” provides evidence for a dose-response relationship between ongoing exposure to this neurotoxic heavy metal—which also plays an important role in the function of the antioxidant enzyme superoxide dismutase—and progression of parkinsonian symptoms.
               
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