A 52-year-old woman with Parkinson disease (PD) since age 42 on carbidopa/levodopa 25/250 5 times/d developed “offs” characterized by left foot dystonia. After adding rasagiline 1 mg/d, multihour episodes of… Click to show full abstract
A 52-year-old woman with Parkinson disease (PD) since age 42 on carbidopa/levodopa 25/250 5 times/d developed “offs” characterized by left foot dystonia. After adding rasagiline 1 mg/d, multihour episodes of gaze deviation, anxiety, retrocollis, and dyskinesias ensued (video, links.lww.com/WNL/A30). Symptoms, marginally improved with diphenhydramine, resolved when levodopa was held temporarily. They did not recur after discontinuation of rasagiline.
               
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