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Author response: Early weight loss in parkinsonism predicts poor outcomes: Evidence from an incident cohort study

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We thank Dr. Marinelli for the comment on our article,1 and agree that further research into the relationship between protein misfolding and weight loss in Parkinson disease (PD) is needed.… Click to show full abstract

We thank Dr. Marinelli for the comment on our article,1 and agree that further research into the relationship between protein misfolding and weight loss in Parkinson disease (PD) is needed. Furthermore, several other potential mechanisms for weight loss deserve further study, including other aspects of brain metabolism, whole-body metabolic rate, appetite regulation, and food-related reward mechanisms.

Keywords: early weight; weight loss; study; response early; author response; loss

Journal Title: Neurology
Year Published: 2018

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