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In this Journal Club article, Bateman et al.1 aimed to explain the mechanisms underlying multiple sclerosis and improving treatment. We would like to make further comments about the use of… Click to show full abstract
In this Journal Club article, Bateman et al.1 aimed to explain the mechanisms underlying multiple sclerosis and improving treatment. We would like to make further comments about the use of gadolinium in the study discussed.2 Patients received a triple recommended dose of a gadolinium-based contrast agent (GBCA) monthly over 12–24 months equaling 72 GBCA doses.2 The study started before the link between gadolinium administrations and increased signal intensity in the dentate nucleus and globus pallidus was discovered in the human brain.3
Journal Title: Neurology
Year Published: 2018
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