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Pearls & Oy-sters: Paroxysmal dysarthria-ataxia syndrome

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Paroxysmal dysarthria-ataxia syndrome (PDA), first described by Parker in 1946, is characterized by paroxysmal and stereotyped repeated daily episodes of sudden ataxic symptoms associated with dysarthric speech lasting from few… Click to show full abstract

Paroxysmal dysarthria-ataxia syndrome (PDA), first described by Parker in 1946, is characterized by paroxysmal and stereotyped repeated daily episodes of sudden ataxic symptoms associated with dysarthric speech lasting from few seconds to minutes.1 During the episodes, patients present with slow speech, irregular articulatory breakdown, dysprosodia, hypernasality, variable pitch and loudness, and prolonged intervals, consistent with perceptual characteristics of ataxic dysarthria.2,3

Keywords: ataxia syndrome; paroxysmal dysarthria; pearls sters; sters paroxysmal; dysarthria ataxia

Journal Title: Neurology
Year Published: 2019

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