I thank Dr. Gupta for the comment on our article.1 Migraine with aura is considered a different clinical entity compared with migraine without aura.2 Pathophysiologically, the 2 are considered to… Click to show full abstract
I thank Dr. Gupta for the comment on our article.1 Migraine with aura is considered a different clinical entity compared with migraine without aura.2 Pathophysiologically, the 2 are considered to be variants, with the accepted notion being that visual aura is generated by cortical spreading depression.3 We have shown that migraine with aura is a risk factor for ischemic stroke of cardioembolic subtype.4 The migraine questionnaire was administered through a structured interview by trained personnel, similar to what a clinician may achieve at the bedside to make migraine with and without aura diagnoses. Studies have shown that migraine with aura is associated with autonomic dysfunction.5 I also wish to thank Dr. Hsieh for identifying the typographical errors in our article.1 In figure 1, the x-axis label should be “Time to incident atrial fibrillation” rather than “Time to stroke.” However, the “log-rank p value” in figure 1 is correct (0.0048).
               
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