Neuromyelitis optica (NMO) spectrum disorder (NMOSD) comprises a group of neuroinflammatory disorders characteristically affecting the optic nerves and the spinal cord. Previously known as Devic disease, NMO was considered a… Click to show full abstract
Neuromyelitis optica (NMO) spectrum disorder (NMOSD) comprises a group of neuroinflammatory disorders characteristically affecting the optic nerves and the spinal cord. Previously known as Devic disease, NMO was considered a variant of multiple sclerosis (MS) until the discovery of anti-aquaporin 4 immunoglobulin G (AQP4-IgG) identified NMO as a separate disease.1 Over the following decade, studies of NMOSD have described with increasing precision the clinical,2 radiologic,3 and neuropathologic4 features.
Journal Title: Neurology
Year Published: 2019
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