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A 24-year-old man presented with gait ataxia, scanning speech, and otherwise unremarkable neurologic examination 4 days after COVID-19 onset (PCR-confirmed, omicron variant). Brain MRI (Figure) revealed cytotoxic lesions of the… Click to show full abstract
A 24-year-old man presented with gait ataxia, scanning speech, and otherwise unremarkable neurologic examination 4 days after COVID-19 onset (PCR-confirmed, omicron variant). Brain MRI (Figure) revealed cytotoxic lesions of the corpus callosum (CLOCC) with secondary involvement of the middle cerebellar peduncles. Worsening in neuroimaging triggered empirical treatment with IVIG after methylprednisolone treatment (1 g-q-24 h/5 d). The patient was neither hypoxic nor required intensive care and clinically improved with resolving neuroimaging findings.
Journal Title: Neurology
Year Published: 2022
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