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Quantifying colocalization: the MOC is a hybrid coefficient – an uninformative mix of co-occurrence and correlation

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Herein, we challenge one of the main conclusions in the Review on colocalization recently published in Journal of Cell Science ([Aaron et al., 2018][1]), that the Manders' overlap coefficient (MOC)… Click to show full abstract

Herein, we challenge one of the main conclusions in the Review on colocalization recently published in Journal of Cell Science ([Aaron et al., 2018][1]), that the Manders' overlap coefficient (MOC) is a valuable coefficient for assessing colocalization by co-occurrence. The underlying theme of the

Keywords: quantifying colocalization; moc hybrid; occurrence; coefficient; colocalization; colocalization moc

Journal Title: Journal of Cell Science
Year Published: 2019

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