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ABSTRACT Manuel Théry graduated from the Ecole Supérieure de Physique et Chimie de la ville de Paris (ESPCI-ParisTech) and the University Paris Diderot, France, with a master in physics and biology interfaces and subsequently obtained his PhD working with Michel Bornens on the control of cell polarity through adhesion at the Institut Curie, Paris. He joined the French Alternative Energies and Atomic Energy Commission (CEA) in Grenoble, France, where he set up the ‘CytoMorphoLab’ together with Laurent Blanchoin. Since 2014, Manuel has directed the Paris unit of this laboratory at the Hôpital Saint Louis, where he investigates the (self-)assembly of the cytoskeleton and how this orchestrates cell geometry and mechanical information in the cell. He has won numerous awards, such as the Claude Paoletti Prize and the ASCB Early Career Award, and has been named an EMBO Young Investigator and is an ERC Starting and Consolidator Grant awardee. Manuel is the Guest Editor for the 2019 Reconstituting Cell Biology Special Issue in Journal of Cell Science.