LAUSR

The standard of care for the management of primary localized retroperitoneal sarcomas (RPS) is a macroscopically complete (R0/R1) surgical resection. This often proves to be technically challenging due to their typically large size and frequent multivisceral involvement. However, durable, long-term local control remains elusive. This has prompted the exploration of a more liberal and extensive resection approach to include adjacent uninvolved organs to reduce local recurrence rates. Significant benefit in local recurrence rates reported by two European centers using this approach has not consistently translated into a benefit in overall survival and, not surprisingly, has resulted in considerable debate. To better define the minimal extent of resection required for primary RPS, our study was designed to provide a descriptive analysis of the rationale for individual organ resection and to examine the rate of histopathologic organ invasion (HOI) among resected organs. PRESENT