LAUSR

Complete pathologic response (cPR) is an independent prognostic variable for improved survival in many cancer types, including gastric cancer. Chemoradiotherapy leads to more cPRs and probably better local control, yet provides less overall survival benefit than chemotherapy alone for different tumors. The authors were intrigued by the survival difference between the patients who achieved a cPR with chemotherapy and those who achieved cPR with chemoradiotherapy. This study used a large national database similar to the National Cancer Database to address this issue in gastric cancer, for which both methods of treatment are used frequently.