Photo by vlisidis from unsplash
An NBD-based fluorescent probe (probe 1) for the detection of Hcy over Cys and GSH based on nucleophilic substitution and Smiles rearrangement reaction was designed and synthesized by the reaction… Click to show full abstract
An NBD-based fluorescent probe (probe 1) for the detection of Hcy over Cys and GSH based on nucleophilic substitution and Smiles rearrangement reaction was designed and synthesized by the reaction of 4-chloro-7-nitro-2,1,3-benzoxadiazole (NBD-Cl) with 1,4-dihydroxybenzene. The probe displayed many desired properties such as high specificity, appreciable solubility, and desirable response time. In addition, probe 1 has low cytotoxicity and detection of intracellular Hcy can be achieved by cell fluorescence imaging.
Keywords:
nbd based;
detection;
probe;
probe detection;
fluorescent turn;
based fluorescent
Journal Title: Chemistry Letters
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Chemistry Letters
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!