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The copper-catalyzed cyanation of aryl iodides is described using nitromethane as a CN source. In situ generation of a “CN” species from nitromethane is plausible. This strategy is an advantageous… Click to show full abstract
The copper-catalyzed cyanation of aryl iodides is described using nitromethane as a CN source. In situ generation of a “CN” species from nitromethane is plausible. This strategy is an advantageous synthetic method for the construction of an aromatic C–CN bond, because nitromethane is a common and easily handled compound that is readily available as a cyanation reagent, and its use allows the avoidance of using toxic metal cyanides.
Keywords:
aryl iodides;
cyanation aryl;
using nitromethane;
cyanation;
catalyzed cyanation;
copper catalyzed
Journal Title: Chemistry Letters
Year Published: 2017
Link to full text (if available)
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Journal Title: Chemistry Letters
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!