A copper-mediated decarboxylative coupling of benzamides with potassium malonate monoesters via 8-aminoquinoline-directed C-H cleavage has been developed. This reaction proceeds only by a copper salt to produce the corresponding alkylation… Click to show full abstract
A copper-mediated decarboxylative coupling of benzamides with potassium malonate monoesters via 8-aminoquinoline-directed C-H cleavage has been developed. This reaction proceeds only by a copper salt to produce the corresponding alkylation products in good yields.
               
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