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A reductive C–C-bond-forming cyclization of vinyl-terminated allyl chlorides via alkene hydroboration with 9-BBN-H followed by Cu-catalyzed asymmetric intramolecular allylic alkylation with a new chiral phosphoramidite ligand produced six-membered ring compounds… Click to show full abstract
A reductive C–C-bond-forming cyclization of vinyl-terminated allyl chlorides via alkene hydroboration with 9-BBN-H followed by Cu-catalyzed asymmetric intramolecular allylic alkylation with a new chiral phosphoramidite ligand produced six-membered ring compounds with a tertiary or quaternary stereogenic center in the ring with high enantioselectivity.
Keywords:
intramolecular alkylboron;
allylic alkylation;
enantioselective intramolecular;
catalyzed enantioselective;
alkylation;
copper catalyzed
Journal Title: Chemistry Letters
Year Published: 2018
Link to full text (if available)
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Journal Title: Chemistry Letters
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!