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Expanding Substrate Specificity of Salicylate Decarboxylase by Site-directed Mutagenesis for Expansion of the Entrance Region Connecting to the Substrate Access Tunnel

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Salicylate decarboxylase (Sdc, EC 4.1.1.91) from the yeast Trichosporon moniliiforme WU-0401 catalyzes the carboxylation of phenol to salicylic acid and is applicable to enzymatic Kolbe-Schmitt rea... Click to show full abstract

Salicylate decarboxylase (Sdc, EC 4.1.1.91) from the yeast Trichosporon moniliiforme WU-0401 catalyzes the carboxylation of phenol to salicylic acid and is applicable to enzymatic Kolbe-Schmitt rea...

Keywords: expanding substrate; salicylate decarboxylase; decarboxylase; specificity salicylate; substrate specificity; decarboxylase site

Journal Title: Chemistry Letters
Year Published: 2019

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