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Synthesis of Seven-membered Ring Containing Difluoromethylene Unit by Sc(OTf)3-catalyzed Activation of Single C–F Bond in CF3 Group

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A Sc(OTf)3-catalyzed activation of a single C–F bond in a CF3 group is described. This reaction has two interesting features: (1) the synthesis of difluoromethylene compounds through Lewis acid-cat... Click to show full abstract

A Sc(OTf)3-catalyzed activation of a single C–F bond in a CF3 group is described. This reaction has two interesting features: (1) the synthesis of difluoromethylene compounds through Lewis acid-cat...

Keywords: cf3 group; single bond; bond cf3; catalyzed activation; otf catalyzed; activation single

Journal Title: Chemistry Letters
Year Published: 2019

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