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Alkylation of Heteroaryl Chlorides through Homolytic Aromatic Substitution by Alkyl Radicals Derived from Alkyl Formates

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The alkylation of heteroaryl chlorides through a homolytic aromatic substitution (HAS) mechanism was achieved by the use of alkyl formates as alkylating agents in the presence of a tert-butoxy radi... Click to show full abstract

The alkylation of heteroaryl chlorides through a homolytic aromatic substitution (HAS) mechanism was achieved by the use of alkyl formates as alkylating agents in the presence of a tert-butoxy radi...

Keywords: heteroaryl chlorides; alkyl formates; homolytic aromatic; aromatic substitution; chlorides homolytic; alkylation heteroaryl

Journal Title: Chemistry Letters
Year Published: 2021

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