ABSTRACT We discuss recent evidence supporting the hypothesis that sarcopenia is an emerging health concern among people with HIV due to increasing life expectancy and HIV- and treatment-related comorbidities. We… Click to show full abstract
ABSTRACT We discuss recent evidence supporting the hypothesis that sarcopenia is an emerging health concern among people with HIV due to increasing life expectancy and HIV- and treatment-related comorbidities. We also hypothesize that combined exercise at higher intensity has a key role in managing sarcopenia in this population because it directly (increases muscle strength and stimulates hypertrophy) and indirectly (prevents mitochondrial dysfunction, oxidative stress and persistent inflammation) counteracts sarcopenia hallmarks.
               
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