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Exercise as a Moderator of Persistent Neuroendocrine Symptoms of COVID-19

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Exercise attenuates the neuropsychiatric and endocrine sequelae of COVID-19 precipitated by chronic psychological stress, immune system dysregulation, and hyperinflammation. Precipitated by chronic psychological stress, immune system dysregulation, and a hyperinflammatory… Click to show full abstract

Exercise attenuates the neuropsychiatric and endocrine sequelae of COVID-19 precipitated by chronic psychological stress, immune system dysregulation, and hyperinflammation. Precipitated by chronic psychological stress, immune system dysregulation, and a hyperinflammatory state, the sequelae of postacute COVID-19 (long COVID) include depression and new-onset diabetes. We hypothesize that exercise counters the neuropsychiatric and endocrine sequelae of long COVID by inducing the release of circulating factors that mediate the anti-inflammatory response, support brain homeostasis, and increase insulin sensitivity.

Keywords: exercise moderator; symptoms covid; neuroendocrine symptoms; persistent neuroendocrine; moderator persistent; exercise

Journal Title: Exercise and Sport Sciences Reviews
Year Published: 2022

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