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Genetic Pathways Underlying Individual Differences in Regular Physical Activity

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Twin and family studies show a strong contribution of genetic factors to physical activity (PA) assessed by either self-report or accelerometers. PA heritability is around 43% across the lifespan. Genome-wide… Click to show full abstract

Twin and family studies show a strong contribution of genetic factors to physical activity (PA) assessed by either self-report or accelerometers. PA heritability is around 43% across the lifespan. Genome-wide association studies have implied biological pathways related to exercise ability and enjoyment. A polygenic score based on genetic variants influencing PA could help improve the success of intervention programs.

Keywords: genetic pathways; individual differences; underlying individual; physical activity; activity; pathways underlying

Journal Title: Exercise and Sport Sciences Reviews
Year Published: 2022

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