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While RNA editing by A-to-I deamination is a requisite for neuronal function in humans, it is under-investigated in single cells. Here we fill this gap by analyzing RNA editing profiles… Click to show full abstract
While RNA editing by A-to-I deamination is a requisite for neuronal function in humans, it is under-investigated in single cells. Here we fill this gap by analyzing RNA editing profiles of single cells from the brain cortex of living human subjects. We show that RNA editing levels per cell are bimodally distributed and distinguish between major brain cell types, thus providing new insights into neuronal dynamics.
Keywords:
single cell;
cell transcriptomics;
rna editing;
transcriptomics reveals;
brain
Journal Title: RNA
Year Published: 2017
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Journal Title: RNA
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!