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Interstitial Granulomatous Dermatitis as an Adverse Reaction to Vedolizumab.

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A 61-year-old woman with a medical history of ulcerative colitis (UC) developed an erythematous, mildly pruritic, maculopapular rash that was histologically consistent with reactive granulomatous dermatitis (RGD) with interstitial granulomatous… Click to show full abstract

A 61-year-old woman with a medical history of ulcerative colitis (UC) developed an erythematous, mildly pruritic, maculopapular rash that was histologically consistent with reactive granulomatous dermatitis (RGD) with interstitial granulomatous dermatitis (IGD)-type features 1 week after vedolizumab infusion. Awareness of this complication is key to enhanced recognition and appropriate management as use of this medication becomes more prevalent.

Keywords: interstitial granulomatous; reaction vedolizumab; dermatitis; dermatitis adverse; adverse reaction; granulomatous dermatitis

Journal Title: Cutis
Year Published: 2022

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