LAUSR

A 36-year-old man with allergic rhinitis presented with lower lip swelling of several months’ duration. The swelling was persistent and predominantly on the left side of the lower lip but occasionally spread to the entire lower lip. The episodes of increased swelling would last for several days and were not associated with any apparent triggers. He denied any pain, pruritus, or dryness. He noted more drooling from the affected side but denied any associated breathing difficulty or throat discomfort. Treatment with an oral antihistamine provided no relief. He denied any recent nonsteroidal anti-inflammatory drug or angiotensinconverting enzyme inhibitor use. His family history was notable for lupus in his maternal grandmother and maternal aunt. He denied any personal or family history of inflammatory bowel disease or recent gastrointestinal tract symptoms. Physical examination revealed nontender edema in the left side of the lower lip with no surface changes. No warmth or erythema were noted. The tongue and the rest of the oral cavity were unremarkable.