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Questioning the evidence for BCI-based communication in the complete locked-in state

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In the following, the statistical analysis is described that was originally performed for the comment, but was replaced with a different analysis after the first review round of the comment.… Click to show full abstract

In the following, the statistical analysis is described that was originally performed for the comment, but was replaced with a different analysis after the first review round of the comment. For each patient separately, the data of all sessions were used and a Wilcoxon's ranksum test was performed for each channel and each sample. The minimum p-value for Patient F was p=0.0026, for Patient G p>0.05, for Patient B p=0.0317, and for Patient W p=0.0109. Due to the large number of tests involved (20 channels with 93 samples equals 1860 tests), the results must be corrected for multiple comparisons. Using a Bonferroni correction with a significance level of α=0.05, the adjusted significance level is α / 1860 = 0.000027, showing that there is no significant difference in the hemodynamic response between "yes" and "no" questions for any of the 4 patients.

Keywords: based communication; bci based; evidence bci; communication complete; questioning evidence; patient

Journal Title: PLoS Biology
Year Published: 2019

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