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Learning from natural variation across the proteomes of single cells

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Biological functions arise from protein interactions, which are reflected in the natural variation of proteome configurations across individual cells. Emerging single-cell proteomics methods may decode this variation and empower inference… Click to show full abstract

Biological functions arise from protein interactions, which are reflected in the natural variation of proteome configurations across individual cells. Emerging single-cell proteomics methods may decode this variation and empower inference of biological mechanisms with minimal assumptions.

Keywords: variation across; learning natural; across proteomes; natural variation; variation; proteomes single

Journal Title: PLoS Biology
Year Published: 2022

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