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Exploring the genetic architecture of protein secretion in Komagataella phaffii (Pichia pastoris) for biotechnology applications

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Improvements to the production of proteins in industrial yeast species have largely relied on generating variation in a single genetic background. A new study in PLOS Biology leverages natural genetic… Click to show full abstract

Improvements to the production of proteins in industrial yeast species have largely relied on generating variation in a single genetic background. A new study in PLOS Biology leverages natural genetic variation to identify genes and variants with the potential to improve protein yield.

Keywords: architecture protein; secretion komagataella; exploring genetic; genetic architecture; protein secretion; biology

Journal Title: PLOS Biology
Year Published: 2022

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