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Computational alanine scanning interface analysis of T = 3 capsids1.

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1 Results from a KFC2 computational alanine scanning interface analysis of the three quasi-equivalent sites (AA, BC, and CB) in the T = 3 capsids described in this study. Residues… Click to show full abstract

1 Results from a KFC2 computational alanine scanning interface analysis of the three quasi-equivalent sites (AA, BC, and CB) in the T = 3 capsids described in this study. Residues identified as hot spots by KFC2 are listed separately for each chain in a dimer. Residues in bold font were classed as high confidence by KFC2. Area and volume values are for the interface region between the two chains, 3 A from each chain, as calculated with FADE (on the KFC2 server) and UCSF Chimera. Note that the CB interface is smaller and that V124 and R127 are not classed as part of the CB interface (boxed cells). (DOCX)

Keywords: interface analysis; computational alanine; scanning interface; alanine scanning; interface

Journal Title: PLOS Computational Biology
Year Published: 2020

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