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The timing of growth faltering has important implications for observational analyses of the underlying determinants of nutrition outcomes

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Background Growth faltering largely occurs in the first 23 months after birth and is thought to be largely determined by various harmful or protective socioeconomic conditions. Children 23 months or… Click to show full abstract

Background Growth faltering largely occurs in the first 23 months after birth and is thought to be largely determined by various harmful or protective socioeconomic conditions. Children 23 months or younger, however, have only been partially exposed to these conditions, implying that statistical associations between these conditions and child growth may be substantially smaller in samples that include younger children. Objectives To test the prediction that associations between child anthropometric outcomes and various socioeconomic conditions are systematically different for older and younger children. Methods We analyzed data for 699,421 children aged 0–59 months, drawn from 125 DHS implemented between 1992 and 2014 in 57 countries. The outcome variables were height-for-age Z scores (HAZ) and stunting (HAZ<-2), and weight-for-height z scores (WHZ) and wasting (WHZ<-2). Independent variables included household wealth, parental education, maternal height, demographic factors, and exposure to WASH and health services. We used age-disaggregated regressions to examine how the associations between dependent and independent variables vary across different child age ranges. Results Non-parametric regression results reaffirmed that most linear growth faltering and wasting takes place prior to 23 months of age. Estimates of the magnitude of association with wealth, education and improved toilet use from HAZ regressions are systematically larger in the sample of children 24–59 months than in the 0–23 month or 0–59 month samples; the reverse is true for WHZ regressions. Conclusions Previous observational analyses appear to substantially underestimate the protective impacts of a wide range of underlying determinants on stunting. Conversely, wasting rates are typically low for children 24–59 months, implying that associations between underlying conditions and wasting may be stronger for children 0–23 months of age. Such analyses should pay closer attention to age disaggregation; researchers should be aware of the age effect reported in the current study and present analysis stratified by age.

Keywords: underlying determinants; observational analyses; age; growth faltering; children months; growth

Journal Title: PLoS ONE
Year Published: 2018

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