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Expression of Concern: Antitumor Activity of Sorafenib in Human Cancer Cell Lines with Acquired Resistance to EGFR and VEGFR Tyrosine Kinase Inhibitors

The original underlying data supporting results in this article are no longer available. The authors replicated the experiments for which concerns were raised using the same methods and conditions as… Click to show full abstract

The original underlying data supporting results in this article are no longer available. The authors replicated the experiments for which concerns were raised using the same methods and conditions as in the original study [1]. Here, they provide updated versions of Figures 1, 3, 5, and 6 that report the replication experiments results, along with underlying data, as Supporting Information files. The authors noted that the replication experiments for Figures 5, 6 were approved by the Second University of Naples Animal Care and Use Committee under approval number IT2017/12187. The PLOS ONE Editors issue this Expression of Concern to notify readers of the issues raised for the published figures and the unavailability of original data for this study.

Keywords: activity sorafenib; sorafenib human; antitumor activity; expression concern; concern; concern antitumor

Journal Title: PLoS ONE
Year Published: 2019

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